Letter by Hartung and Cottrell regarding article, "What is the use of hypothermia for neuroprotection after out-of-hospital cardiac arrest?".
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چکیده
منابع مشابه
Effects of mild hypothermia on expression of NF-E2-related factor 2 and heme-oxygenase-1 in cerebral cortex and hippocampus after cardiopulmonary resuscitation in rats
Objective(s): The aim of this study was to investigate the effects of mild hypothermia on expression of NF-E2-related factor 2 (Nrf2) and heme-oxygenase-1 (HO-1) of rat cerebral cortex and hippocampus after cardiopulmonary resuscitation and further investigate the possible mechanism of action. Material and Methods:To copy an asphyxia heart arrest model, Sprague Dawley rats were randomly divided...
متن کاملTherapeutic hypothermia after cardiac arrest in adults: mechanism of neuroprotection, phases of hypothermia, and methods of cooling.
Sudden cardiac arrest is the main manifestation of ischemic heart diseases, which is the leading cause of death worldwide. Each year an estimated 300,000 people suffer from cardiac arrest in the United States, with a variable incidence ranging from 36/100,000 to 128/100,000. Approximately 7.9% of cardiac arrest victims survive to hospital discharge in the United States, whereas fewer than half ...
متن کاملWhat is the use of hypothermia for neuroprotection after out-of-hospital cardiac arrest?
O ut-of-hospital cardiac arrest (OHCA) refers to the loss of cardiac mechanical activity with hemodynamic collapse in the out-of-hospital setting. If not treated rapidly, OHCA invariably results in death. Survival to hospital discharge after OHCA is low in many communities, ranging between 10.7% (95% confidence interval, 9.9%–11.5%) for adults treated for all rhythms and 31.7% (95% confidence i...
متن کاملLetter by Guo et al Regarding Article, "Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest: A Randomized, Controlled Study".
To the Editor: We read with great interest the recent article by Deye et al concerning “Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest.” Their excellent study on this important subject deserves applause. However, we have some concerns about the strength of their conclusion that endovascular cooling was not significantly superior to ...
متن کاملMild hypothermia during advanced life support: a preliminary study in out-of-hospital cardiac arrest
INTRODUCTION Induction of mild hypothermia after cardiac arrest may confer neuroprotection. We assessed the feasibility, safety and effectiveness of therapeutic infusion of 2 l of normal saline at 4 degrees C before return of spontaneous circulation during cardiopulmonary resuscitation after out of hospital cardiac arrest. METHODS This was a prospective, observational, multicenter clinical tr...
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ورودعنوان ژورنال:
- Stroke
دوره 46 4 شماره
صفحات -
تاریخ انتشار 2015